The 796,223-acre Sewee to Santee region extends along approximately 35 miles of coastline, from Dewees Inlet to the North Santee River. The immediate coastal portion of this region consists of eight undeveloped barrier islands with numerous tidal inlets and is backed by 73,000 acres of salt and brackish marshes and intertidal mud flats. It includes the Santee River Delta with 20,000 acres of managed wetlands. The western portion of the region is dominated by the Francis Marion National Forest, which supports extensive longleaf pine and bottomland hardwood forests. Overall, the Sewee to Santee region has a rich diversity of natural systems and native species, including resident and migratory waterfowl, shorebirds, songbirds, and endangered species. To date, the Conservancy has helped to protect 37,137 acres in the Sewee to Santee region.